Meds That Treat Anxiety Anxiety is among the most common mental health issues that affects 40 million adults in the United States. It's extremely treatable with numerous medications available. SSRIs (selective serotonin reuptake inhibitors) and SNRIs (serotonin-norepinephrine reuptake inhibitors), like Zoloft, Prozac, Lexapro and Effexor, work to alleviate anxiety by